Appraise individuals for indications of urinary retention or lowered gastric motility when OXYCONTIN is used concomitantly with anticholinergic medicine.
Screen clients for danger of material use disorders, including opioid abuse and misuse, and warn them of the danger for overdose and Demise affiliated with the use of extra CNS depressants such as Liquor and illicit medications [see Drug Interactions (seven)].
Go over The provision of naloxone to the emergency remedy of opioid overdose With all the individual and caregiver and evaluate the opportunity want for entry to naloxone, each when initiating and renewing treatment method with OXYCONTIN [see Warnings and Safety measures (5.2)].
• Do not just take in excess of forty mg of OxyContin in a single dose or more than 80 mg of OxyContin in someday Until you are “opioid tolerant.” This might cause you to halt respiration and may lead to Loss of life.
Acceptable studies carried out thus far have not shown geriatric-particular issues that might Restrict the usefulness of oxycodone during the aged.
Conversion from Other Opioids to OXYCONTIN When OXYCONTIN therapy is initiated, discontinue all other opioid analgesics in addition to Those people utilised on an as needed foundation for breakthrough discomfort when suitable.
The risk for critical breathing complications is larger when You begin this medication and after a dose improve, or if you are taking the incorrect dose/power. Getting this medication with Liquor or other medication that can result in drowsiness or respiration difficulties may well induce extremely critical Unwanted effects, together with Loss read more of life. Also, other prescription drugs can influence the removal of oxycodone from your human body, which may have an affect on how oxycodone will work.
Abuse of oral dosage types by parenteral administration might be envisioned to bring about severe adverse functions, such as local tissue necrosis, infection, pulmonary granulomas, elevated danger of endocarditis, and valvular coronary heart damage, which may be fatal.
o to control pain immediately after surgical procedures In the event the soreness is delicate and isn't envisioned to last for an extended length of time
Observe infants subjected to OXYCONTIN by way of breast milk for excessive sedation and respiratory despair. Withdrawal signs can arise in breast-fed infants when maternal administration of an opioid analgesic is stopped, or when breast-feeding is stopped.
When this medication is utilised for a long time, it may well not do the job in addition. Speak with your health practitioner if this medication stops Doing the job properly.
If making use of asymmetric dosing, instruct sufferers to take the higher dose each morning and also the lessen dose from the night.
When this medication is used for a long time, it may well not perform in addition. Speak with your doctor if this medication stops Functioning nicely.
Adults—Just one tablet just about every twelve hours. The whole amount of milligrams (mg) daily is similar to the full quantity of regular oxycodone that's taken each day. The overall amount of money each day will likely be presented as two divided doses throughout the day. Your doctor might modify your dose as necessary.